Prime BSI & Prime BSI Express | Low Noise sCMOS Cameras

Sensor Technology

sCMOS

Quantum Efficiency

95%

Readout Noise

1.0 e-

Resolution

6.5 µm x 6.5 µm pixels

Speed

63 FPS (at 11-bit)

Interface

PCle, USB 3.0

The Prime BSI & BSI Express Scientific CMOS (sCMOS) cameras deliver the perfect balance between high resolution imaging and sensitivity with an optimized pixel design and near perfect 95% Quantum Efficiency.

The Prime BSI Express is a compact 78mm x 78mm x 90mm with optimized cooling for the size, ideal for integration into new or existing configurations.

Key Features

Sensitivity

The Prime BSI back-illuminated sCMOS camera achieves a near-perfect 95% quantum efficiency. By bringing the light in from the back of the sensor, photons land directly onto the light receiving surface, maximizing light collecting capability. The Prime BSI combines 95% quantum efficiency with a low 1.0 e- read noise to deliver the most sensitive camera based on sCMOS technology at over 40 frames per second.

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Resolution and Pixel Size

The Prime BSI features 6.5 μm pixels, the accepted standard for most live cell applications using 40x and 60x magnification. This pixel size provides highly detailed images across the imaging plane and is most suitable for the broadest range of microscope objectives.

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Superior Background Quality

The Prime BSI features Pattern Noise Reduction Technology and Correlated Noise Reduction Technology to ensure that it delivers clean, pattern free images with minimal pixel defects, delivering improved image quality in low light conditions.

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Advanced Triggering

Programmable Scan Mode provides increased control over the rolling shutter exposure and read-out functionality of CMOS sensors for applications that require control over the line time.

Sequenced Multiple Acquisition Real Time Streaming (SMART) Streaming enables the Prime BSI to capture a continuous sequence of images while cycling through 16 pre-programmed exposure time values, delivering the fastest multi-channel acquisition times.

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Advanced Features

The Prime BSI offers PrimeEnhance active denoising which provides a real-time quantitative increase in the signal to noise ratio to maximize sensitivity at ultra-low light levels.

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Model	Prime BSI	Prime BSI Express
Sensor	Gpixel GSense2020 BSI Scientific CMOS Sensor	Gpixel GSense2020 BSI Scientific CMOS Sensor
Camera Dimensions	108.39 mm x 108.39 mm x 162.07 mm	78 mm x 78 mm x 92 mm
Active Array Size	2048 x 2048 (4.2 mp)	2048 x 2048 (4.2 mp)
Quantum Efficiency	>95%	>95%
Pixel Area	6.5 µm x 6.5 µm (42.25 µm2)	6.5 µm x 6.5 µm (42.25 µm2)
Sensor Area	13.3 mm x 13.3 mm, 18.8 mm diagonal	13.3 mm x 13.3 mm, 18.8 mm diagonal
Readout Noise	1.0 e-	1.0 e-
Full-Well Capacity	45,000 e- (combined gain) 10,000 e- (high gain) 1,000 e- (CMS)	45,000 e- (combined gain) 10,000 e- (high gain) 1,000 e- (CMS)
Frame rate (full-frame)	63 fps at 11-bit	63 fps at 11-bit
Bit Depth	16-bit (combined gain) 12-bit (CMS) 11-bit (high gain)	16-bit (combined gain) 12-bit (CMS) 11-bit (high gain)
Readout Mode	Rolling Shutter Effective Global Shutter Programmable Scan Mode (PCI-E only)	Rolling Shutter Effective Global Shutter Programmable Scan Mode (PCI-E only)
Binning	2×2 (on FPGA)	2×2 (on FPGA)
Interface	PCle, USB 3.0	USB 3.2 Gen 2
Linearity	>99.5%	>99.5%

TIRF Microscopy
Ratiometric Imaging
Cell Motility
Light Sheet Microscopy

Data Sheet

PrimeBSI Datasheet

Prime BSI Express Datasheet

Manual & Handbook

Prime BSI Manual

Prime BSI Handbook

Description
Additional information

The Prime BSI large field of view Scientific CMOS (sCMOS) camera delivers the perfect balance between high resolution imaging and sensitivity with an optimized pixel design and near perfect 95% Quantum Efficiency.

95% Quantum Efficiency
6.5 µm x 6.5 µm Pixel Area
1 e- Read Noise

The Prime BSI Express is a compact 78mm x 78mm x 90mm with optimized cooling for the size, ideal for integration into new or existing configurations.

Key Features

Sensitivity

> Learn More

Resolution and Pixel Size

The Prime BSI large field of view scmos features 6.5 μm pixels, the accepted standard for most live cell applications using 40x and 60x magnification. This pixel size provides highly detailed images across the imaging plane and is most suitable for the broadest range of microscope objectives.

> Learn More

Superior Background Quality

> Learn More

Advanced Triggering

Programmable Scan Mode provides increased control over the rolling shutter exposure and read-out functionality of CMOS sensors for applications that require control over the line time.

> Learn More

Advanced Features

The Prime BSI offers PrimeEnhance active denoising which provides a real-time quantitative increase in the signal to noise ratio to maximize sensitivity at ultra-low light levels.

Learn More

For a similar product, check out the Prime 95B | Low Noise sCMOS Camera

Applications	Life Science
Manufacturer	Photometrics
Sensor Technology	sCMOS
Spectral Range	UV (200 – 400 nm), VIS (400 – 750 nm), NIR (750 – 1000 nm)
Resolution	2048 x 2048 (4.2 MP)
Pixel Pitch	6.5 µm x 6.5 µm
Frame Rate	10 – 100 fps
Readout Noise	1 – 2 e-
Interface	USB, PCIe

Prime BSI & Prime BSI Express | Low Noise sCMOS Cameras